Certified Hospice and Palliative Assistant (CHPNA) Practice Test 2026 - Free CHPNA Exam Practice Questions and Preparation Guide

Nonsteroidal anti-inflammatory drugs (NSAIDs) have been associated with an increased risk of cardiovascular events, including myocardial infarction (heart attack) and stroke. This risk is particularly significant in individuals who may already be at risk due to existing cardiovascular conditions or other risk factors such as age, hypertension, or a history of heart disease.

NSAIDs function by blocking cyclooxygenase (COX) enzymes, which leads to reduced synthesis of prostaglandins involved in inflammation and pain. However, prostaglandins also play a key role in maintaining cardiovascular homeostasis. By inhibiting these compounds, NSAIDs can lead to adverse cardiovascular effects, such as increased blood pressure, fluid retention, and potential adverse effects on the heart's performance.

Understanding the implications of NSAID use is crucial for healthcare professionals, especially when prescribing these medications to at-risk populations where careful consideration of benefits versus risks must be assessed.